A Simplified Diagnostic Classification Scheme of Chemotherapy-Induced Peripheral Neuropathy.

ABSTRACT: Background and Objective. The main purpose of this study was to develop a simple automatic diagnostic classification scheme for chemotherapy-induced peripheral neuropathy.

Methods

This was a prospective cohort study that enrolled patients with colorectal or gynecologic cancer post chemotherapy for more than 1 year. The patients underwent laboratory examinations (nerve conduction studies and quantitative sensory tests), and a questionnaire about the quality of life. An unsupervised classification algorithm was used to classify the patients into groups using a small number of variables derived from the laboratory tests. A panel of five neurologists also diagnosed the types of neuropathies according to the laboratory tests. The results by the unsupervised classification algorith

SUBMITTER: Huang HW 

PROVIDER: S-EPMC7008270 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature