Familial occurrence of mitral regurgitation in patients with mitral valve prolapse undergoing mitral valve surgery.

ABSTRACT:

Background

Initial studies have suggested the familial clustering of mitral valve prolapse, but most of them were either community based among unselected individuals or applied non-specific diagnostic criteria. Therefore little is known about the familial distribution of mitral regurgitation in a referral-type population with a more severe mitral valve prolapse phenotype. The objective of this study was to evaluate the presence of familial mitral regurgitation in patients undergoing surgery for mitral valve prolapse, differentiating patients with Barlow's disease, Barlow forme fruste and fibro-elastic deficiency.

Methods

A total of 385 patients (62 ± 12 years, 63% men) who underwent surgery for mitral valve prolapse were contacted to assess cardiac family history systematica

SUBMITTER: Hiemstra YL 

PROVIDER: S-EPMC7008556 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature