Pain management protocol implementation and opioid consumption in critical care: an interrupted time series analysis.

ABSTRACT:

Objective

To evaluate the impact of an opioid-sparing pain management protocol on overall opioid consumption and clinical outcomes.

Methods

This was a single-center, quasi-experimental, retrospective, before and after cohort study. We used an interrupted time series to analyze changes in the levels and trends of the utilization of different analgesics. We used bivariate comparisons in the before and after cohorts as well as logistic regression and quantile regression for adjusted estimates.

Results

We included 988 patients in the preintervention period and 1,838 in the postintervention period. Fentanyl consumption was slightly increasing before the intervention (β = 16; 95%CI 7 - 25; p = 0.002) but substantially decreased in level with the intervention (β = - 128; 95%

SUBMITTER: Besen BAMP 

PROVIDER: S-EPMC7009002 | biostudies-literature | 2019 Oct-Dec

REPOSITORIES: biostudies-literature