Re-evaluation of propane-1,2-diol alginate (E 405) as a food additive.

ABSTRACT: The present opinion deals with the re-evaluation of propane-1,2-diol alginate (E 405) when used as a food additive. The Panel noted that absorption, distribution, metabolism and excretion (ADME) data on propane-1,2-diol alginate gave evidence for the hydrolysis of this additive into propane-1,2-diol and alginic acid. These two compounds have been recently re-evaluated for their safety of use as food additives (EFSA ANS Panel, 2017, 2018). Consequently, the Panel considered in this opinion the major toxicokinetic and toxicological data of these two hydrolytic derivatives. No adverse effects were reported in subacute and subchronic dietary studies with propane-1,2-diol alginate. The available data did not indicate a genotoxic concern for propane-1,2-diol alginate (E 405) when used as a food

SUBMITTER: EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) 

PROVIDER: S-EPMC7009538 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature