Cannabis use during methadone maintenance treatment for opioid use disorder: a systematic review and meta-analysis.

ABSTRACT:

Background

Rates of cannabis use among patients receiving methadone maintenance therapy are high, and cannabis use may be associated with outcomes of methadone maintenance therapy. We examined the effect of cannabis use on opioid use in patients receiving methadone maintenance therapy to test the hypothesis that cannabis use is associated with a reduction in opioid use.

Methods

In this systematic review, we searched MEDLINE/PubMed, Embase, PsycINFO, CINAHL and ProQuest Dissertations and Theses Global from inception to July 12, 2018. We summarized the effects of cannabis use on opioid use during methadone maintenance therapy and treatment retention. We conducted meta-analyses using a random effects model.

Results

We included 23 studies in our review. We performed a met

SUBMITTER: McBrien H 

PROVIDER: S-EPMC7010349 | biostudies-literature | 2019 Oct-Dec

REPOSITORIES: biostudies-literature