Threat bias and resting state functional connectivity of the amygdala and bed nucleus stria terminalis.

ABSTRACT:

Background

Previous research has distinguished the activations of the amygdala and bed nucleus of stria terminalis (BNST) during threat-related contingencies. However, how intrinsic connectivities of the amygdala and BNST relate to threat bias remains unclear. Here, we investigated how resting state functional connectivity (rsFC) of the amygdala and BNST in healthy controls (HC) and patients with anxiety-related disorders (PAD) associate with threat bias in a dot-probe task.

Methods

Imaging and behavioral data of 30 PAD and 83 HC were obtained from the Nathan Kline Institute - Rockland sample and processed according to published routines. All imaging results were evaluated at voxel p < 0.001 and cluster p < 0.05, FWE corrected in SPM.

Results

PAD and HC did not show d

SUBMITTER: Jenks SK 

PROVIDER: S-EPMC7010552 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature