Copper and Melanin Play a Role in Myxococcus xanthus Predation on Sinorhizobium meliloti.

ABSTRACT: Myxococcus xanthus is a soil myxobacterium that exhibits a complex lifecycle with two multicellular stages: cooperative predation and development. During predation, myxobacterial cells produce a wide variety of secondary metabolites and hydrolytic enzymes to kill and consume the prey. It is known that eukaryotic predators, such as ameba and macrophages, introduce copper and other metals into the phagosomes to kill their prey by oxidative stress. However, the role of metals in bacterial predation has not yet been established. In this work, we have addressed the role of copper during predation of M. xanthus on Sinorhizobium meliloti. The use of biosensors, variable pressure scanning electron microscopy, high-resolution scanning transmission electron microscopy, and energ

SUBMITTER: Contreras-Moreno FJ 

PROVIDER: S-EPMC7010606 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature