Association between vertebral fractures and coronary artery calcification in current and former smokers in the ECLIPSE cohort.

ABSTRACT: In smokers and former smokers from the ECLIPSE cohort, there is an association between prevalent vertebral fractures (VFs) and coronary artery calcification (CAC). Chest CT scans provide the opportunity to evaluate VFs and CAC, which are potentially important comorbidities, each of which is amenable to effective interventions.

Introduction

Prevalence of VFs among smokers and patients with chronic obstructive pulmonary disease (COPD) is high, and an association between CAC and osteoporosis has been described. We investigated the associations between VFs and CAC (expressed in Agatston score) in (former) smokers.

Methods

Current and former smokers from the ECLIPSE study (designed to determine underlying COPD progression mechanisms) were studied. Baseline Agatston score (zero (0)

SUBMITTER: van Dort MJ 

PROVIDER: S-EPMC7010611 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature