Modification of the head proteome of nurse honeybees (Apis mellifera) exposed to field-relevant doses of pesticides.

ABSTRACT: Understanding the effect of pesticides on the survival of honeybee colonies is important because these pollinators are reportedly declining globally. In the present study, we examined the changes in the head proteome of nurse honeybees exposed to individual and combined pesticides (the fungicide pyraclostrobin and the insecticide fipronil) at field-relevant doses (850 and 2.5 ppb, respectively). The head proteomes of bees exposed to pesticides were compared with those of bees that were not exposed, and proteins with differences in expression were identified by mass spectrometry. The exposure of nurse bees to pesticides reduced the expression of four of the major royal jelly proteins (MRJP1, MRJP2, MRJP4, and MRJP5) and also several proteins associated with carbohydrate metabolism and energ

SUBMITTER: Zaluski R 

PROVIDER: S-EPMC7010795 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature