Pharmacological vs Exercise Stress Echocardiography for Detection of Cardiac Allograft Vasculopathy.

ABSTRACT:

Objective

To test the hypothesis that exercise and dobutamine would provide levels of cardiac stress that are comparable to those achieved in a general stress test population, and to one another, in heart transplant recipients.

Patients and methods

From February 10, 2015, to December 31, 2017, 81 patients underwent exercise stress (N=45) or dobutamine stress (N=36) echocardiography at a mean ± SD of 11±14 years (range, 1-29 years) after heart transplant. Hemodynamic and inotropic responses were compared between groups, and to a prior test, longitudinally. The primary outcome was peak heart rate (HR) × systolic blood pressure (SBP).

Results

Peak exercise HR × SBP × 10^-3 was a mean ± SD of 24.9±4.9 mm Hg/min for exercise stress vs 21.2±3.4 mm Hg/min during do

SUBMITTER: Gebska MA 

PROVIDER: S-EPMC7011003 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature