Cardio-Respiratory Fitness and Autonomic Function in Patients with Major Depressive Disorder.

ABSTRACT: Patients with major depressive disorder (MDD) have an augmented risk of cardiovascular morbidity and mortality. Although a link between depression and autonomic dysfunction as well as reduced cardio-respiratory fitness (CRF) is well documented, the underlying cause is a matter of debate. Therefore, we studied the interplay between autonomic function, body composition and severity of the disease to disentangle possible physiological factors influencing the assumed lack of CRF in MDD patients. We investigated seventeen patients suffering from MDD and seventeen control subjects matched with respect to age, sex, body-mass-index, and smoking habits. A resting baseline assessment and a cardiopulmonary exercise test including a prolonged recovery period were performed to study autonomic function

SUBMITTER: Herbsleb M 

PROVIDER: S-EPMC7011194 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature