Characterizing lineage-specific evolution and the processes driving genomic diversification in chordates.

ABSTRACT:

Background

Understanding the origins of genome content has long been a goal of molecular evolution and comparative genomics. By examining genome evolution through the guise of lineage-specific evolution, it is possible to make inferences about the evolutionary events that have given rise to species-specific diversification. Here we characterize the evolutionary trends found in chordate species using The Adaptive Evolution Database (TAED). TAED is a database of phylogenetically indexed gene families designed to detect episodes of directional or diversifying selection across chordates. Gene families within the database have been assessed for lineage-specific estimates of dN/dS and have been reconciled to the chordate species to identify retained duplicates. Gene families have also be

SUBMITTER: Northover DE 

PROVIDER: S-EPMC7011509 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature