The effects of omega-3 fatty acids on diabetic nephropathy: A meta-analysis of randomized controlled trials.

ABSTRACT: OBJECTIVE:To evaluate the effects of omega-3 long-chain polyunsaturated fatty acids on proteinuria, estimated glomerular filtration rate (eGFR) and metabolic biomarkers among patients with diabetes. STUDY DESIGN:Meta-analysis of randomized controlled clinical trials (RCTs). SETTING & SUBJECTS:Patients with diabetes. SELECTION CRITERIA FOR STUDIES:We conducted electronic searches in PubMed, Embase and Cochrane Central Register of Controlled Trials from January 1960 to April 2019 to identify RCTs, which examined the effects of omega-3 fatty acids on proteinuria, eGFR and metabolic biomarkers among diabetic patients. RESULTS:Ten RCTs with 344 participants were included in our meta-analysis. Omega-3 fatty acids reduced the amount of proteinuria among type 2 diabetes mellitus (type 2 DM) and ty

SUBMITTER: Chewcharat A 

PROVIDER: S-EPMC7012392 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature