Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up.

ABSTRACT: Biological age measurements (BAs) assess aging-related physiological change and predict health risks among individuals of the same chronological age (CA). Multiple BAs have been proposed and are well studied individually but not jointly. We included 845 individuals and 3973 repeated measurements from a Swedish population-based cohort and examined longitudinal trajectories, correlations, and mortality associations of nine BAs across 20 years follow-up. We found the longitudinal growth of functional BAs accelerated around age 70; average levels of BA curves differed by sex across the age span (50-90 years). All BAs were correlated to varying degrees; correlations were mostly explained by CA. Individually, all BAs except for telomere length were associated with mortality risk independently of

SUBMITTER: Li X 

PROVIDER: S-EPMC7012595 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature