Perimenstrual Asthma in Aspirin-Exacerbated Respiratory Disease.

ABSTRACT:

Background

Aspirin-exacerbated respiratory disease (AERD) is a condition of the upper and lower respiratory tract characterized by reactions to nonsteroidal anti-inflammatory drugs. The Severe Asthma Research Program reported a strong association between perimenstrual asthma (PMA) and aspirin-sensitive asthma.

Objective

To evaluate the prevalence and characteristics of PMA among a cohort of patients with AERD.

Methods

Women 18 years and older enrolled in the Brigham and Women's AERD registry were surveyed about their reproductive, asthma, and sinus history. Subjects reporting the development of asthma before menopause were included. Continuous and categorical variables were compared between those reporting menstruation as a trigger for asthma symptoms and those who di

SUBMITTER: Eid RC 

PROVIDER: S-EPMC7012664 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature