Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers.

ABSTRACT:

Objective

It is unclear why Black smokers in the United States have elevated risk of some tobacco-related diseases compared to White smokers. One possible causal mechanism is differential intake of tobacco toxicants, but results across studies are inconsistent. Thus, we examined racial differences in biomarkers of toxic volatile organic compounds (VOCs) present in tobacco smoke.

Method

We analyzed baseline data collected from 182 Black and 184 White adult smokers who participated in a randomized clinical trial in 2013-2014 at 10 sites across the United States. We examined differences in urinary levels of ten VOC metabolites, total nicotine equivalents (TNE), and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), controlling for covariates such as cigarettes per day (CPD),

SUBMITTER: St Helen G 

PROVIDER: S-EPMC7012700 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature