Effect of the Application of a Dehydrothermal Treatment on the Structure and the Mechanical Properties of Collagen Film.

ABSTRACT: Dehydrothermal (DHT) treatment was used to improve the properties of collagen casings because of its non-cytotoxicity. Understanding the effects of DHT treatment on the structure and mechanical properties of collagen films is beneficial to developing satisfying collagen casings. Herein, DHT treatment with various temperatures (85-145 °C) and timescales (1-7 days) were investigated. It was clarified that the chemical crosslinking covalent bond between collagen molecules was formed after the DHT treatment. Crosslinking density increased with increasing DHT treatment temperatures, contributing to the increase of tensile strength up to over three times of that of the untreated collagen film. The increased crosslinking density was also found when increasing the DHT treatment time, and the maxim

SUBMITTER: Chen X 

PROVIDER: S-EPMC7013574 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature