Association between cumulative social risk, particulate matter environmental pollutant exposure, and cardiovascular disease risk.

ABSTRACT: BACKGROUND:Long-term exposure to pollution has been shown to increase risk of cardiovascular disease (CVD) and mortality, and may contribute to the increased risk of CVD among individuals with higher social risk. METHODS:Data from the community-based Heart Strategies Concentrating on Risk Evaluation (HeartSCORE) study were used to quantify Cumulative Social Risk (CSR) by assigning a score of 1 for the presence of each of 4 social risk factors: racial minority, single living, low income, and low educational status. 1-year average air pollution exposure to PM2.5 was estimated using land-use regression models. Associations with clinical outcomes were assessed using Cox models, adjusting for traditional CVD risk factors. The primary clinical outcome was combined all-cause mortality and nonfata

SUBMITTER: Canterbury A 

PROVIDER: S-EPMC7014734 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature