Extremely Low Frequency Magnetic Fields Do Not Affect LTP-Like Plasticity in Healthy Humans.

ABSTRACT:

Introduction

Several studies explored the biological effects of extremely low-frequency magnetic fields (ELF-MFs) in vitro, reporting the induction of functional changes in neuronal activity. In particular, ELF-MFs can influence synaptic plasticity both in vitro and in animal models but some studies reported an increase in long-term potentiation (LTP) whereas others suggested its reduction. However, no specific study has investigated such effect on humans.

Aims

To evaluate whether ELF-MFs affect the propensity of the human cortex to undergo LTP-like plasticity.

Methods

We designed a randomized, single-blind, sham-controlled, cross-over study on 10 healthy subjects. Cortical plasticity was induced by intermittent theta burst stimulation (iTBS) before and

SUBMITTER: Capone F 

PROVIDER: S-EPMC7014826 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature