Association of Sleep Apnea with Mortality in Patients with Advanced Kidney Disease.

ABSTRACT:

Background and objectives

In the general population, sleep disorders are associated with mortality. However, such evidence in patients with CKD and ESKD is limited and shows conflicting results. Our aim was to examine the association of sleep apnea with mortality among patients with CKD and ESKD.

Design, setting, participants, & measurements

In this prospective cohort study, 180 patients (88 with CKD stage 4 or 5, 92 with ESKD) underwent in-home polysomnography, and sleep apnea measures such as apnea hypopnea index (AHI) and nocturnal hypoxemia were obtained. Mortality data were obtained from the National Death Index. Cox proportional hazard models were used for survival analysis.

Results

Among the 180 patients (mean age 54 years, 37% women, 39% with diabetes, 49% CKD

SUBMITTER: Jhamb M 

PROVIDER: S-EPMC7015094 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature