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Reproducibility of Deceased Donor Kidney Procurement Biopsies.


ABSTRACT:

Background and objectives

Unfavorable histology on procurement biopsies is the most common reason for deceased donor kidney discard. We sought to assess the reproducibility of procurement biopsy findings.

Design, setting, participants, & measurements

We compiled a continuous cohort of deceased donor kidneys transplanted at our institution from 1/1/2006 to 12/31/2016 that had at least one procurement biopsy performed, and excluded cases with missing biopsy reports and those used in multiorgan transplants. Suboptimal histology was defined as the presence of advanced sclerosis in greater than or equal to one biopsy compartment (glomeruli, tubules/interstitium, vessels). We calculated κ coefficients to assess agreement in optimal versus suboptimal classification between s

SUBMITTER: Husain SA 

PROVIDER: S-EPMC7015101 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature