Unraveling virus relationships by structure-based phylogenetic classification.
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ABSTRACT:
SUBMITTER: Ng WM
PROVIDER: S-EPMC7015158 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Publications
Unraveling virus relationships by structure-based phylogenetic classification.
Ng Weng M WM Stelfox Alice J AJ Bowden Thomas A TA
Virus evolution 20200101 1
Delineation of the intricacies of protein function from macromolecular structure constitutes a continual obstacle in the study of cell and pathogen biology. Structure-based phylogenetic analysis has emerged as a powerful tool for addressing this challenge, allowing the detection and quantification of conserved architectural properties between proteins, including those with low or no detectable sequence homology. With a focus on viral protein structure, we highlight how a number of investigations ...[more]
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