Preoperative Risk and the Association between Hypotension and Postoperative Acute Kidney Injury.

ABSTRACT:

Background

Despite the significant healthcare impact of acute kidney injury, little is known regarding prevention. Single-center data have implicated hypotension in developing postoperative acute kidney injury. The generalizability of this finding and the interaction between hypotension and baseline patient disease burden remain unknown. The authors sought to determine whether the association between intraoperative hypotension and acute kidney injury varies by preoperative risk.

Methods

Major noncardiac surgical procedures performed on adult patients across eight hospitals between 2008 and 2015 were reviewed. Derivation and validation cohorts were used, and cases were stratified into preoperative risk quartiles based upon comorbidities and surgical procedure. After preoperat

SUBMITTER: Mathis MR 

PROVIDER: S-EPMC7015776 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature