How Do PET Myocardial Blood Flow Reserve and FFR Differ?

ABSTRACT: PURPOSE OF REVIEW:This review discusses similarities and differences between cardiac positron emission tomography (PET), absolute myocardial blood flow, and flow reserve with invasive fractional flow reserve (FFR). RECENT FINDINGS:Fundamentally, cardiac PET measures absolute myocardial blood flow whereas FFR provides a relative flow reserve. Cardiac PET offers a non-invasive and therefore lower risk alternative, able to image the entire left ventricle regardless of coronary anatomy. While cardiac PET can provide unique information about the subendocardium, FFR pullbacks offer unparalleled spatial resolution. Both diagnostic tests provide a highly repeatable and technically successful index of coronary hemodynamics that accounts for the amount of distal myocardial mass, albeit only indirect

SUBMITTER: Johnson NP 

PROVIDER: S-EPMC7015869 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature