Fracture-related infections in HIV infected patients: A systematic review and meta-analysis.

ABSTRACT:

Aim

To conduct a systematic review and meta-analysis comparing the incidence of fracture-related infections (FRI) following surgical management of closed and open fractures in HIV-positive and HIV-negative patients.

Methods

A systematic literature search was conducted using MEDLINE, ProQuest, Web of Science, The Cochrane Library and Scopus. Our own files and reference lists of identified key articles were also searched. We included studies where the primary outcome was the development of FRI in patients with open and closed fractures.

Results

Eleven studies were included for data synthesis. HIV-positive patients had a non-significant increase in FRI when compared to HIV-negative patients (in open and closed fractures combined). Open fractures treated in the pre-antire

SUBMITTER: Nieuwoudt L 

PROVIDER: S-EPMC7016040 | biostudies-literature | 2020 Mar-Apr

REPOSITORIES: biostudies-literature