Resting-State Functional Correlates of Social Cognition in Multiple Sclerosis: An Explorative Study.

ABSTRACT: Social cognition includes mental operations essential for functional social interactions, and several studies revealed an impairment of social cognition abilities in patients with Multiple Sclerosis (MS). These deficits have been related to global and focal gray matter atrophy as well as microstructural white matter damage. Although some studies reveal a correlation between social cognition and task-based functional magnetic resonance imaging (MRI), no studies to date have explored the association between brain resting-state functional connectivity (RS-FC) abnormalities and several measures of social cognition in MS. The aim of this explorative study was to assess the contribution of RS-FC abnormalities of major brain networks to social cognition in MS patients. Clinical, neuropsychologica

SUBMITTER: Bisecco A 

PROVIDER: S-EPMC7016209 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature