Inference of Breed Structure in Farm Animals: Empirical Comparison between SNP and Microsatellite Performance.

ABSTRACT: Knowledge of population structure is essential to improve the management and conservation of farm animal genetic resources. Microsatellites, which have long been popular for this type of analysis, are more and more neglected in favor of whole-genome single nucleotide polymorphism (SNP) chips that are now available for the main farmed animal species. In this study, we compared genetic patterns derived from microsatellites to that inferred by SNPs, considering three pairs of datasets of sheep and cattle. Population genetic differentiation analyses (Fixation index, F_ST), as well as STRUCTURE analyses showed a very strong consistency between the two types of markers. Microsatellites gave pictures that were largely concordant with SNPs, although less accurate. The best concordance wa

SUBMITTER: Laoun A 

PROVIDER: S-EPMC7016564 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature