Morphology-Controlled Self-Assembly and Synthesis of Biopolyimide Particles from 4-Amino-l-phenylalanine.

ABSTRACT: Self-assembling polyimides (PIs) having diketopiperazine (DKP) components were synthesized by polycondensation of a 4-amino-l-phenylalanine (4APhe) dimer, an aromatic diamine newly designed in this study. The amino acid-derived PIs showed high thermal resistance, with a 10% weight loss temperature (T d10) of 432 °C at the maximum, and did not show any glass transition below the thermal decomposition temperature. The poly(amic acid) (PAA) precursors formed nanospheres upon reprecipitation over dimethylacetamide into water. The nanospheres were then added to solvents with different polarities and sonicated to induce deformation of the spherical forms into spiky balls, flakes, or rods. The PAA particle morphologies were retained in the PIs after the two-step imidization. Finally, the PI parti

SUBMITTER: Hirayama T 

PROVIDER: S-EPMC7016914 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature