The impact on incident tuberculosis by kidney function impairment status: analysis of severity relationship.

ABSTRACT: BACKGROUND:The risk of tuberculosis (TB) in patients with impaired kidney function remains unclear by different stages of renal function impairment. METHODS:We retrospectively recruited all patients with kidney function in a tertiary-care referral center from January 2008 to December 2013 and followed them till December 2016. We defined the primary outcome as active TB development and analyzed the impact of kidney function impairment. RESULTS:During the study period, a total of 289,579 patients were enrolled for analysis, and of them, 1012 patients had active TB events in an average of 4.13 years of follow-up. According to kidney function impairment, the incidence rate of TB was similar in patients with no chronic kidney disease (CKD) or stage 1 and stage 2, and it increased apparently at

SUBMITTER: Shu CC 

PROVIDER: S-EPMC7017479 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature