Impact of bariatric surgery on cerebral vascular reactivity and cognitive function: a non-randomized pilot study.

ABSTRACT:

Background

Bariatric surgery is an effective long-term weight loss strategy yielding improvements in neurocognitive function; however, the mechanism(s) responsible for these improvements remains unclear. Here, we assessed the feasibility of using magnetic resonance imaging (MRI) to evaluate whether cerebral vascular reactivity (CVR) is impaired in severely obese bariatric surgery candidates compared with normal weight healthy controls and whether CVR improves following bariatric surgery. We also investigated whether changes in CVR were associated with changes in cognitive function.

Methods

Bariatric surgery candidates (n = 6) were compared with normal weight healthy controls of a similar age (n = 10) at baseline, and then reassessed 2 weeks and 14 weeks followi

SUBMITTER: Tucker WJ 

PROVIDER: S-EPMC7017515 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature