The complex neurobiology of resilient functioning after childhood maltreatment.

ABSTRACT:

Background

Childhood maltreatment has been associated with significant impairment in social, emotional and behavioural functioning later in life. Nevertheless, some individuals who have experienced childhood maltreatment function better than expected given their circumstances.

Main body

Here, we provide an integrated understanding of the complex, interrelated mechanisms that facilitate such individual resilient functioning after childhood maltreatment. We aim to show that resilient functioning is not facilitated by any single 'resilience biomarker'. Rather, resilient functioning after childhood maltreatment is a product of complex processes and influences across multiple levels, ranging from 'bottom-up' polygenetic influences, to 'top-down' supportive social influences. We h

SUBMITTER: Ioannidis K 

PROVIDER: S-EPMC7017563 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature