Is the bispectral index monitoring protective against postoperative cognitive decline? A systematic review with meta-analysis.

ABSTRACT:

Background

Several studies have suggested that monitoring the depth of anaesthesia might prevent the development of postoperative cognitive decline. We aimed to conduct a meta-analysis to investigate the effects of bispectral index (BIS) monitoring in anaesthesia.

Methods

We searched in six major electronic databases. Trials were included if they discussed anaesthesia with and without BIS monitoring or low (<50) and high (≥50) BIS levels and which measured the risk of postoperative delirium (POD) and/or postoperative cognitive dysfunction (POCD).

Results

We included fourteen studies in the systematic review, eight of which were eligible for meta-analysis. BIS proved to be protective against POD at 1 day postoperatively in a cohort of 2138 patients (16.1% vs. 22.8% for

SUBMITTER: Bocskai T 

PROVIDER: S-EPMC7018011 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature