Epidemiology of Staphylococcus aureus in neonates on admission to a Chinese neonatal intensive care unit.

ABSTRACT:

Purpose

Little is known about the molecular epidemiology of Staphylococcus aureus in Chinese neonatal intensive care units (NICUs). We describe the molecular epidemiology of S. aureus isolated from neonates on admission to Beijing Children's Hospital.

Methods

From May 2015-March 2016, nasal swabs were obtained on admission from 536 neonates. Cultures were also obtained from body sites with suspected infections. S. aureus isolates were characterized by staphylococcal chromosomal cassette (SCCmec) type, staphylococcal protein A (spa) type, multilocus sequence type (MLST), sasX gene, antimicrobial susceptibility and cytotoxicity. Logistic regression assessed risk factors for colonization.

Results

Overall, 92 (17%) infants were colonized with S. aureus and 20 (3.7%) were

SUBMITTER: Geng W 

PROVIDER: S-EPMC7018019 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature