Cognitively unimpaired adults' reactions to disclosure of amyloid PET scan results.

ABSTRACT:

Importance

Clinical guidelines currently recommend against amyloid imaging for cognitively unimpaired persons. The goal of Alzheimer's disease (AD) prevention, together with advances in understanding the pathophysiology of AD, however, has led to trials testing drugs in cognitively unimpaired persons who show evidence of AD biomarkers. Assuming the eventual success of such trials, millions of patients will be affected. There is a need to understand the effects of biomarker disclosure on those individuals.

Design

The Study of Knowledge and Reactions to Amyloid Testing (SOKRATES) involved 2 semi-structured telephone interviews with individuals who received amyloid PET scan results as part of screening for research participation. Post-disclosure interviews were conducted at 4 t

SUBMITTER: Largent EA 

PROVIDER: S-EPMC7018056 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature