Effect of dilutional anemia that can be treated with only one unit of red blood cell transfusion on tissue oxygenation in cardiac surgery patients

ABSTRACT:

Background/aim

Cardiac surgery, especially in the presence of cardiopulmonary bypass (CPB), is associated with an inflammatory reaction that may promote microcirculatory alterations, in addition to the general impact on system hemodynamics. Anemia and transfusion make patients more susceptible to the deleterious effects of CPB. In this study, it was aimed to evaluate the effect of dilutional anemia, which is caused by CPB and can be treated with 1–2 units of red blood cell (RBC) transfusion, on global tissue oxygenation parameters in cardiac surgery patients.

Materials and methods

This prospective observational study comprised 127 patients who had a relatively stable operation period without any major anesthetic or surgical com

SUBMITTER: Tezcan 

PROVIDER: S-EPMC7018202 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature