Health State Utility Data in Cystic Fibrosis: A Systematic Review.

ABSTRACT:

Introduction

Cystic fibrosis (CF) is a life-limiting, hereditable condition, with the highest prevalence in Europe. CF treatments have led to improvements in clinical symptoms, disease management and decelerated disease progression. However, little is known about the health state utility (HSU) associated with CF disease states, adverse events, and changes in disease severity. Although HSU data have contributed to existing health economic modelling studies, a lack of such data have been highlighted. This systematic review aims to provide a summary of HSU-related research in CF and highlight related research gaps.

Methods

Online searches were performed in six databases and studies in any of the following categories were included: (1) estimation of HSUs in CF; (2) mapping studi

SUBMITTER: Mohindru B 

PROVIDER: S-EPMC7018933 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature