Methacrylate Coatings for Titanium Surfaces to Optimize Biocompatibility.

ABSTRACT: Currently, there are more than 1.5 million knee and hip replacement procedures carried out in the United States. Implants have a 10-15-year lifespan with up to 30% of revision surgeries showing complications with osteomyelitis. Titanium and titanium alloys are the favored implant materials because they are lightweight and have high mechanical strength. However, this increased strength can be associated with decreased bone density around the implant, leading to implant loosening and failure. To avoid this, current strategies include plasma-spraying titanium surfaces and foaming titanium. Both techniques give the titanium a rough and irregular finish that improves biocompatibility. Recently, researchers have also sought to surface-conjugate proteins to titanium to induce osteointegration. Ce

SUBMITTER: Sun A 

PROVIDER: S-EPMC7019220 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature