3D Printed Multi-Functional Hydrogel Microneedles Based on High-Precision Digital Light Processing.

ABSTRACT: Traditional injection and extraction devices often appear painful and cumbersome for patients. In recent years, polymer microneedles (MNs) have become a novel tool in the field of clinical medicine and health. However, the cost of building MNs into any shapes still remains a challenge. In this paper, we proposed hydrogel microneedles fabricated by high-precision digital light processing (H-P DLP) 3D printing system. Benefits from the sharp protuberance and micro-porous of the hydrogel microneedle, the microneedle performed multifunctional tasks such as drug delivery and detection with minimally invasion. Critical parameters for the fabrication process were analyzed, and the mechanical properties of MNs were measured to find a balance between precision and stiffness. Results shows that the

SUBMITTER: Yao W 

PROVIDER: S-EPMC7019295 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature