[Bipolar disorder vulnerability: The vitamin D path].

ABSTRACT:

Objectives

Bipolar disorder (BD) etiopathogenesis is still not well elucidated. It has recently been proven that 25-hydroxy vitamin D (25OHD) has an anti-inflammatory and neuroprotective role. Our objectives were to measure 25OHD plasma levels in patients with BD in acute decompensation and compare them with patients with schizophrenia (SCZ) or schizoaffective disorder (SAD) and with healthy controls.

Methods

This is a cross-sectional case-control study including male inpatients with a decompensation of their disease who were diagnosed with BD, SCZ or SAD according to DSM-5 criterias. The control group was constituted by unrelated healthy subjects, age-and-sex matched.

Results

The 25OHD level was significantly higher only in patients with BD compared to controls. 25OH

SUBMITTER: Naifar M 

PROVIDER: S-EPMC7019462 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature