Microtubules in Influenza Virus Entry and Egress.

ABSTRACT: Influenza viruses are respiratory pathogens that represent a significant threat to public health, despite the large-scale implementation of vaccination programs. It is necessary to understand the detailed and complex interactions between influenza virus and its host cells in order to identify successful strategies for therapeutic intervention. During viral entry, the cellular microenvironment presents invading pathogens with a series of obstacles that must be overcome to infect permissive cells. Influenza hijacks numerous host cell proteins and associated biological pathways during its journey into the cell, responding to environmental cues in order to successfully replicate. The cellular cytoskeleton and its constituent microtubules represent a heavily exploited network during viral infec

SUBMITTER: Simpson C 

PROVIDER: S-EPMC7020094 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature