Added Value of Impact Microindentation in the Evaluation of Bone Fragility: A Systematic Review of the Literature.

ABSTRACT: The current gold standard for the diagnosis of osteoporosis and the prediction of fracture risk is the measurement of bone mineral density (BMD) using dual energy x-ray absorptiometry (DXA). A low BMD is clearly associated with increased fracture risk, but BMD is not the only determinant of bone strength, particularly in secondary osteoporosis and metabolic bone disorders in which components other than BMD are affected and DXA often underestimates true fracture risk. Material properties of bone which significantly contribute to bone strength have become evaluable in vivo with the impact microindentation (IMI) technique using the OsteoProbe® device. The question arises whether this new tool is of added value in the evaluation of bone fragility. To this effect, we conducted a systemat

SUBMITTER: Schoeb M 

PROVIDER: S-EPMC7020781 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature