Toxicity of the organophosphate insecticide sumithion to embryo and larvae of zebrafish.

ABSTRACT: Sumithion, a synthetic organophosphate, is widely used as an agricultural insecticide and for control of tiger bug (Cicindela spp.) in larval rearing for aquaculture. An experiment was conducted to examine the effects of sumithion on embryological and larval development of zebrafish Danio rerio. Fertilized egg (n = 100) and larvae (n = 100) were exposed to six concentrations of sumithion (0, 0.1, 0.2, 0.4, 0.8 and 1.6 mg L-1) in three replicates. LC50 values for embryos and larvae were calculated by probit analysis. The 24 h LC50 value of sumithion for embryo was 0.235 (0.079-0.428) mgL-1. Increasing sumithion concentrations decreased hatching success and increased embryonic mortality. In embryos, sumithion induced several malformations including immature yolk sac, dark yolk sac, yolk sac

SUBMITTER: Rahman MS 

PROVIDER: S-EPMC7021556 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature