Comparing the interobserver reproducibility of different regions of interest on multi-parametric renal magnetic resonance imaging in healthy volunteers, patients with heart failure and renal transplant recipients.

ABSTRACT:

Objective

To assess interobserver reproducibility of different regions of interest (ROIs) on multi-parametric renal MRI using commercially available software.

Materials and methods

Healthy volunteers (HV), patients with heart failure (HF) and renal transplant recipients (Tx) were recruited. Localiser scans, T1 mapping and pseudo-continuous arterial spin labelling (pCASL) were performed. HV and Tx also underwent diffusion-weighted imaging to allow calculation of apparent diffusion coefficient (ADC). For T1, pCASL and ADC, ROIs were drawn for whole kidney (WK), cortex (Cx), user-defined representative cortex (rep-Cx) and medulla. Intraclass correlation coefficient (ICC) and coefficient of variation (CoV) were assessed.

Results

Forty participants were included (10 HV, 10

SUBMITTER: Rankin AJ 

PROVIDER: S-EPMC7021749 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature