Mechanical Properties and Cytotoxicity of Differently Structured Nanocellulose-hydroxyapatite Based Composites for Bone Regeneration Application.

ABSTRACT: The nanocomposites were prepared by synthesizing (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO)-oxidized cellulose nanofibrils (TCNFs) or cellulose nanocrystals (CNCs) with hydroxyapatite (HA) in varying composition ratios in situ. These nanocomposites were first obtained from eggshell-derived calcium and phosphate of ammonium dihydrogen orthophosphate as precursors at a stoichiometric Ca/P ratio of 1.67 with ultrasonication and compressed further by a uniaxial high-pressure technique. Different spectroscopic, microscopic, and thermogravimetric analyses were used to evaluate their structural, crystalline, and morphological properties, while their mechanical properties were assessed by an indentation method. The contents of TCNF and CNC were shown to render the formation of the HA crystall

SUBMITTER: Ingole VH 

PROVIDER: S-EPMC7022391 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature