Cupriavidus sp. HN-2, a Novel Quorum Quenching Bacterial Isolate, is a Potent Biocontrol Agent Against Xanthomonas campestris pv. campestris.

ABSTRACT: Diffusible signal factor (DSF) represents a family of widely conserved quorum sensing (QS) signals involved in the regulation of virulence factor production in many Gram-negative bacterial pathogens. Quorum quenching, which disrupts QS either by degradation of QS signals or interference of signal generation or perception, is a promising strategy for prevention and control of QS-mediated bacterial infections. In this study, a novel DSF-degrading strain, HN-2, was isolated from contaminated soil and identified as Cupriavidus sp. The isolate exhibited superior DSF degradation activity and completely degraded 2 mmol·L^-1 of DSF within 24 h. Analysis of the degradation products of DSF by gas chromatography-mass spectrometry led to the identification of trans-2-decenoic acid met

SUBMITTER: Ye T 

PROVIDER: S-EPMC7022395 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature