Antioxidant Activity of Metal Nanoparticles Coated with Tocopherol-Like Residues-The Importance of Studies in Homo- and Heterogeneous Systems.

ABSTRACT: Functionalized nanoparticles (NPs) attract great attention in pharmacy, diagnostics, and biomedical areas due to benefits like localization and unique interactions of NPs with biocomponents of living cells. In the present paper, we prepared and characterized two kinds of gold nanoparticles (AuNPs) coated with α-tocopherol-like residues: 1A were soluble in non-polar solvents and their antioxidant activity was tested during the peroxidation of a model hydrocarbon in a homogeneous system, whereas nanoparticles 1B were soluble in polar solvents and were applied as antioxidants in micellar and liposomal systems. The effectiveness of 1A is comparable to 2,2,5,7,8-pentamethylchroman-6-ol (PMHC, an analogue of α-tocopherol). Taking the results of the kinetic measurements, we calculated an average

SUBMITTER: Konopko A 

PROVIDER: S-EPMC7022694 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature