Metabolomic Profiling of Fungal Pathogens Responsible for Root Rot in American Ginseng.

ABSTRACT: Ginseng root is an economically valuable crop in Canada at high risk of yield loss caused by the pathogenic fungus Ilyonectria mors-panacis, formerly known as Cylindrocarpon destructans. While this pathogen has been well-characterized from morphological and genetic perspectives, little is known about the secondary metabolites it produces and their role in pathogenicity. We used an untargeted tandem liquid chromatography-mass spectrometry (LC-MS)-based approach paired with global natural products social molecular networking (GNPS) to compare the metabolite profiles of virulent and avirulent Ilyonectria strains. The ethyl acetate extracts of 22 I. mors-panacis strains and closely related species were analyzed by LC-MS/MS. Principal component analysis of LC-MS feat

SUBMITTER: DesRochers N 

PROVIDER: S-EPMC7023087 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature