Antifouling Napyradiomycins from Marine-Derived Actinomycetes Streptomyces aculeolatus.

ABSTRACT: The undesired attachment of micro and macroorganisms on water-immersed surfaces, known as marine biofouling, results in severe prevention and maintenance costs (billions €/year) for aquaculture, shipping and other industries that rely on coastal and off-shore infrastructures. To date, there are no sustainable, cost-effective and environmentally safe solutions to address this challenging phenomenon. Therefore, we investigated the antifouling activity of napyradiomycin derivatives that were isolated from actinomycetes from ocean sediments collected off the Madeira Archipelago. Our results revealed that napyradiomycins inhibited ≥80% of the marine biofilm-forming bacteria assayed, as well as the settlement of Mytilus galloprovincialis larvae (EC₅₀ < 5 µg/ml and LC₅₀

SUBMITTER: Pereira F 

PROVIDER: S-EPMC7024211 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature