Identifying critical windows of prenatal particulate matter (PM_2.5) exposure and early childhood blood pressure.

ABSTRACT:

Background

Exposure to air pollution is associated with increased blood pressure (BP) in adults and children. Some evidence suggests that air pollution exposure during the prenatal period may contribute to adverse cardiorenal health later in life. Here we apply a distributed lag model (DLM) approach to identify critical windows that may underlie the association between prenatal particulate matter ≤ 2.5 μm in diameter (PM_2.5) exposure and children's BP at ages 4-6 years.

Methods

Participants included 537 mother-child dyads enrolled in the Programming Research in Obesity, GRowth Environment, and Social Stress (PROGRESS) longitudinal birth cohort study based in Mexico City. Prenatal daily PM_2.5 exposure was estimated using a validated satellite-based spati

SUBMITTER: Rosa MJ 

PROVIDER: S-EPMC7024649 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature