Treatment of Intermediate-Stage Hepatocellular Carcinoma in Japan: Position of Curative Therapies.

ABSTRACT:

Background

Transcatheter arterial chemoembolization (TACE) is the standard therapy for intermediate-stage (IM) hepatocellular carcinoma (HCC). However, IM-HCC includes various clinical conditions, and various therapies were conducted in practice. In this study, we retrospectively analyzed the actually conducted treatments for IM-HCC and their efficacies to elucidate the treatment strategies suitable for IM-HCC.

Methods

This study included 627 IM-HCC of 5,260 HCC from 9 hospitals. We examined the treatment strategies of these patients and analyzed the efficacy of each therapy with the Cox proportional hazard model and propensity score-matched analysis.

Results

Liver resection, radiofrequency ablation (RFA), and TACE were performed in 165, 108, and 351 patients, respect

SUBMITTER: Kariyama K 

PROVIDER: S-EPMC7024876 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature